⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2730082 | 0.71 | — | — | |
| SCHEMBL28010930 | 0.59 | — | — | |
| SCHEMBL18327710 | 0.57 | — | — | |
| SCHEMBL279520 | 0.57 | — | — | |
| SCHEMBL932677 | 0.57 | — | — | |
| SCHEMBL15614937 | 0.56 | — | — | |
| SCHEMBL7624224 | 0.55 | — | — | |
| SCHEMBL2540204 | 0.54 | — | — | |
| SCHEMBL23263210 | 0.52 | — | — | |
| SCHEMBL388290 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4058455-A1 | NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE | Temple University - Of The Commonwealth System of Higher Education (US) | 2022-09-21 | — | — | EP | disclosed |
| WO-2013027168-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS BROMODOMAIN INHIBITORS | PFIZER INC. (US) | 2013-02-28 | — | — | WO | disclosed |
| US-5185338-A | Medicament for treating cerebral insufficiency diseases, novel 2-(1-piperazinyl)-4-phenylcycloalkanopyrimidine derivatives, and process for the production thereof | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| US-5041443-A | Medicament for treating cerebral insufficiency diseases, novel 2-(1-piperazinyl)-4-phenylcycloalkanopyrimidine derivatives, and process for the production thereof | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |