SCHEMBL9559031

SCHEMBL9559031

CC(C)C(COCc1cccc(Oc2ccc(F)cc2)c1)c1ccc(OC(F)F)cc1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.39
CETP P11597 2/20 0.37
FFAR1 O14842 2/20 0.36
FDFT1 P37268 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PPARA Q07869 2/20 0.35
PPARG P37231 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
TACR1 P25103 2/20 0.34
RXRA P19793 2/20 0.34
GRIN1 Q05586 2/20 0.34
GRIN2B Q13224 2/20 0.34
MPO P05164 1/20 0.33
DAO P14920 1/20 0.33
GPR139 Q6DWJ6 1/20 0.33
ACACB O00763 1/20 0.33
ACACA Q13085 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10837299 0.81 MRGPRX4 (0.35) MRGPRX4FFAR1MEN1KMT2APPARA
SCHEMBL9558361 0.81 KDM4E (0.51) MRGPRX4FFAR1MEN1KMT2ATACR1
SCHEMBL9558733 0.79 FFAR1 (0.45) CETPFFAR1FFAR4TACR1
SCHEMBL9558968 0.79 FFAR1 (0.52) MRGPRX4CETPFFAR1FFAR4ACACB
SCHEMBL9558288 0.78 PPARG (0.46) MRGPRX4FFAR1PPARAPPARGTACR1
SCHEMBL10851816 0.78 CETP (0.40) MRGPRX4CETPFDFT1PPARAPPARG
SCHEMBL10607542 0.76 CETP (0.42) MRGPRX4CETPFFAR1PPARAPPARG
SCHEMBL10547516 0.76 FDFT1 (0.46) FFAR1FDFT1MEN1KMT2APPARA
SCHEMBL27267314 0.75 FFAR4 (0.46) CETPFFAR1FDFT1FFAR4MPO
SCHEMBL10858151 0.74 CETP (0.38) MRGPRX4CETPFFAR1FDFT1PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed