SCHEMBL95596

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8539894	0.89	MAPT (0.53)	S1PR4MRGPRX4MAPTL3MBTL1TDP1
	SCHEMBL8903264	0.86	MAPT (0.60)	S1PR4MRGPRX4MAPTL3MBTL1TDP1
	SCHEMBL2091304	0.86	MRGPRX4 (0.49)	S1PR4MRGPRX4MAPTL3MBTL1TDP1
	SCHEMBL9217899	0.84	MAPT (0.54)	S1PR4MRGPRX4MAPTL3MBTL1TDP1
	SCHEMBL8358491	0.83	MAPT (0.50)	S1PR4MRGPRX4MAPTL3MBTL1TDP1
	SCHEMBL8358492	0.83	MAPT (0.53)	S1PR4MRGPRX4MAPTL3MBTL1TDP1
	SCHEMBL2004375	0.83	S1PR4 (0.51)	S1PR4MRGPRX4MAPTL3MBTL1TDP1
	SCHEMBL6608879	0.82	CA12 (0.61)	MAPTHPGDMEN1ALDH1A1KMT2A
	SCHEMBL11565117	0.81	MAPT (0.51)	S1PR4MRGPRX4MAPTL3MBTL1TDP1
	SCHEMBL8536866	0.81	MAPT (0.51)	S1PR4MRGPRX4MAPTL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.