Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 19/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27829924 | 0.95 | TOP1 (0.81) | TOP1MEN1KMT2A | |
| SCHEMBL5649602 | 0.95 | TOP1 (0.81) | TOP1MEN1KMT2A | |
| SCHEMBL9559944 | 0.93 | TOP1 (0.76) | TOP1MEN1KMT2A | |
| SCHEMBL31681864 | 0.93 | TOP1 (0.76) | TOP1MEN1KMT2A | |
| SCHEMBL25402642 | 0.93 | TOP1 (0.71) | TOP1MEN1KMT2A | |
| SCHEMBL29878282 | 0.93 | TOP1 (0.71) | TOP1MEN1KMT2A | |
| SCHEMBL9559760 | 0.92 | TOP1 (0.74) | TOP1MEN1KMT2A | |
| SCHEMBL18296783 | 0.90 | TOP1 (0.80) | TOP1MEN1KMT2A | |
| SCHEMBL9559965 | 0.90 | TOP1 (0.80) | TOP1MEN1KMT2A | |
| SCHEMBL17092808 | 0.90 | TOP1 (0.74) | TOP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325247-B1 | CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-5061800-A | ANTITUMOR AGENTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0325247-A1 | Camptothecin derivatives and process for preparing same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1989-07-26 | — | — | EP | disclosed |