Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 10/20 | 0.78 |
| ▸ | AKR1C2 | P52895 | 10/20 | 0.78 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.78 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.78 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | CDC42 | P60953 | 1/20 | 0.65 |
| ▸ | RAC1 | P63000 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3043390 | 0.88 | AKR1C3 (1.00) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 | |
| SCHEMBL505820 | 0.88 | AKR1C3 (1.00) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 | |
| SCHEMBL32670173 | 0.88 | AKR1C3 (1.00) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 | |
| SCHEMBL32670176 | 0.88 | AKR1C3 (1.00) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 | |
| SCHEMBL506301 | 0.88 | AKR1C3 (1.00) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 | |
| SCHEMBL24991971 | 0.88 | AKR1C3 (1.00) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 | |
| SCHEMBL15535590 | 0.86 | AKR1C3 (0.76) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 | |
| SCHEMBL8812788 | 0.86 | AKR1C3 (0.76) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 | |
| SCHEMBL220267 | 0.85 | AKR1C3 (0.70) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 | |
| SCHEMBL490727 | 0.85 | AKR1C3 (0.55) | AKR1C3AKR1C2PTGS1AKR1C1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992001062-A1 | PROCESS FOR PRODUCING ENANTIOMERS OF 2-ARYL-ALKANOIC ACIDS | NOVO NORDISK A/S (DK) | 1992-01-23 | — | — | WO | claimed |
| EP-0537259-A1 | PROCESS FOR PRODUCING ENANTIOMERS OF 2-ARYL-ALKANOIC ACIDS | NOVO NORDISK A/S (DK) | 1993-04-21 | — | — | EP | disclosed |
| WO-1992001062-A1 | PROCESS FOR PRODUCING ENANTIOMERS OF 2-ARYL-ALKANOIC ACIDS | NOVO NORDISK A/S (DK) | 1992-01-23 | — | — | WO | disclosed |