SCHEMBL9560307

SCHEMBL9560307

C=CCON=C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
ALDH1A1 P00352 2/20 0.36
GAA P10253 1/20 0.36
MEN1 O00255 1/20 0.33
FAAH O00519 1/20 0.33
ABHD16A O95870 1/20 0.33
KMT2A Q03164 1/20 0.33
PLA2G7 Q13093 1/20 0.33
NCEH1 Q6PIU2 1/20 0.33
DAGLB Q8NCG7 1/20 0.33
DAGLA Q9Y4D2 1/20 0.33
TSHR P16473 1/20 0.32
CASP1 P29466 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3281966 0.79 CHRM2 (0.36) CHRM2CHRM1ALDH1A1
SCHEMBL16233609 0.76 CHRM2 (0.41) CHRM2CHRM1ALDH1A1
SCHEMBL7541983 0.75 KMT2A (0.36) ALDH1A1GAAMEN1FAAHABHD16A
SCHEMBL9132833 0.75 MEN1 (0.36) MEN1FAAHABHD16AKMT2APLA2G7
SCHEMBL3083566 0.74 MEN1 (0.31) ALDH1A1GAAMEN1FAAHABHD16A
SCHEMBL14278390 0.72 CHRM2 (0.32) CHRM2CHRM1
SCHEMBL12465180 0.72
SCHEMBL9133421 0.72
SCHEMBL10628195 0.71 CHRM2 (0.33) CHRM2CHRM1
Cyclohexanone Oxime SCHEMBL28336732 0.71 TSHR (0.56) ALDH1A1GAAMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0194554-B1 PROCESS FOR PRODUCTION OF OXIME DERIVATIVES NIPPON ZEON CO., LTD. (JP) 1993-09-01 EP disclosed
US-4906768-A Process for production of oxime derivatives NIPPON ZEON CO., LTD. (JP) 1990-03-06 US disclosed
EP-0194554-A2 Process for production of oxime derivatives NIPPON ZEON CO., LTD. (JP) 1986-09-17 EP disclosed
EP-0121701-A1 Process for the production of o-substituted oximes ALLIED CORPORATION (US) 1984-10-17 EP disclosed