Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560562 | 0.99 | RARB (0.55) | RARBSMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL9560697 | 0.99 | RARB (0.55) | RARBSMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL9560736 | 0.96 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL9560280 | 0.96 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL9560374 | 0.96 | RARB (0.51) | RARBSMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL9560436 | 0.95 | RARB (0.53) | RARBSMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL9560765 | 0.95 | RARB (0.53) | RARBSMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL9560767 | 0.95 | RARB (0.53) | RARBSMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL9560493 | 0.95 | RARB (0.53) | RARBSMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL9561040 | 0.95 | RARB (0.53) | RARBSMN1; SMN2MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190688-A | Perfluoroalkyl Compounds Dopes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0300009-B1 | LIQUID CRYSTALLINE MIXTURE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |