Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | NSD3 | Q9BZ95 | 5/20 | 0.44 |
| ▸ | NSD2 | O96028 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.40 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8446150 | 0.87 | PNP (0.51) | ADORA2AADORA1FGFR1SLC22A6 | |
| SCHEMBL10889158 | 0.84 | ADORA2A (0.68) | ADORA2AADORA1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL7812370 | 0.80 | ADORA2A (0.63) | ADORA2AADORA1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL10362340 | 0.79 | ADORA2A (0.61) | ADORA2AADORA1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL9561541 | 0.73 | HPRT1 (0.63) | — | |
| SCHEMBL28770510 | 0.73 | ADORA2A (0.47) | ADORA2AADORA1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL6013391 | 0.73 | ADORA2A (0.64) | ADORA2AADORA1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL20404701 | 0.71 | ENPP1 (0.43) | ADORA2AADORA1FGFR1SLC22A6LMNA | |
| Hydrochloric Acid SCHEMBL10890931 | 0.71 | NSD3 (0.43) | ADORA2AADORA1FGFR1SLC22A6NSD3 | |
| SCHEMBL10582562 | 0.71 | PNP (0.50) | ADORA2AADORA1FGFR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346460-B1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION (IT) | 1993-03-10 | — | — | EP | disclosed |
| EP-0346460-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION. | CO PHARMA CORP SRL (IT) | 1989-12-20 | — | — | EP | disclosed |
| WO-1989005818-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION S.R.L. (IT) | 1989-06-29 | — | — | WO | disclosed |