Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.60 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26193728 | 0.95 | RARB (0.55) | RARBGPR3PSMB5HSD11B1RARA | |
| SCHEMBL9398982 | 0.90 | RARB (0.68) | RARBGPR3RARARARGPTGS2 | |
| SCHEMBL2909950 | 0.89 | RARB (0.64) | RARBGPR3HSD11B1RARARARG | |
| SCHEMBL9223658 | 0.89 | RARB (0.50) | RARBGPR3PSMB5HSD11B1RARA | |
| SCHEMBL10981922 | 0.89 | RARB (0.70) | RARBGPR3RARARARGPTGS2 | |
| SCHEMBL10974728 | 0.89 | RARB (0.70) | RARBGPR3RARARARGPTGS2 | |
| SCHEMBL10979477 | 0.89 | RARB (0.70) | RARBGPR3RARARARGPTGS2 | |
| SCHEMBL10975095 | 0.89 | RARB (0.70) | RARBGPR3RARARARGPTGS2 | |
| SCHEMBL10977018 | 0.89 | RARB (0.70) | RARBGPR3RARARARGPTGS2 | |
| SCHEMBL10976338 | 0.89 | RARB (0.70) | RARBGPR3RARARARGPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61246156-A | — | — | None | — | — | JP | disclosed |
| CN-108251127-A | Liquid crystal compound containing difluoromethoxy bridge bond and application thereof | 北京八亿时空液晶科技股份有限公司 | 2018-07-06 | — | — | CN | disclosed |
| CN-108130101-A | Liquid crystal compound containing difluoromethoxy bridge bond and application thereof | 北京八亿时空液晶科技股份有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-104513115-B | The manufacture method of fluorine-containing aryl-linking compound | 大金工业株式会社 | 2017-09-19 | — | — | CN | disclosed |
| CN-107011920-A | Liquid crystal media comprising thiophene derivant | 默克专利股份有限公司 | 2017-08-04 | — | — | CN | disclosed |
| CN-104837956-A | Liquid-crystalline medium | MERCK PATENT GMBH | 2015-08-12 | — | — | CN | disclosed |
| CN-103571498-B | CF2S bridged bond-containing liquid crystal monomeric compound and synthesis method | XI AN CAIJING OPTO ELECTRICAL SCIENCE & TECHNOLOGY CO LTD | 2015-06-17 | — | — | CN | disclosed |
| CN-104513115-A | Process for producing fluorine-containing biaryl compound | DAIKIN IND LTD | 2015-04-15 | — | — | CN | disclosed |
| CN-104449761-A | Liquid crystal compound containing difluoromethoxy bridge bond and application thereof | JIANG ZHANYING | 2015-03-25 | — | — | CN | disclosed |
| CN-104326952-A | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL CO | 2015-02-04 | — | — | CN | disclosed |
| CN-104277004-A | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL CO | 2015-01-14 | — | — | CN | disclosed |
| EP-0530338-A1 | ANISOTROPIC ORGANIC COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) | 1993-03-10 | — | — | EP | disclosed |
| EP-0215120-B1 | CYCLOHEXANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1989-08-23 | — | — | EP | disclosed |
| US-4846998-A | LIQUID CRYSTALS, ESTERS, NITRILES; ETHERS, HYDROCARBONS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-07-11 | — | — | US | disclosed |
| EP-0215120-A1 | CYCLOHEXANE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1987-03-25 | — | — | EP | disclosed |
| JP-S61246156-A | 1-ACYLAMIDO-2-FLUORO-4-ACYLBENZENE AND PRODUCTION THEREOF | SAGAMI CHEM RES CENTER | 1986-11-01 | — | — | JP | disclosed |
| WO-1986005486-A1 | CYCLOHEXANE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-09-25 | — | — | WO | disclosed |