Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562765 | 1.00 | MAPT (0.41) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL9562406 | 0.97 | MAPT (0.39) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL9562403 | 0.97 | MAPT (0.39) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL9406074 | 0.96 | GAA (0.39) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL9406079 | 0.96 | GAA (0.39) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL9562441 | 0.96 | MAPT (0.42) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL9562443 | 0.96 | MAPT (0.42) | MAPTGAALMNAMAPK1HTT | |
| SCHEMBL9562416 | 0.95 | MEN1 (0.39) | MAPTGAAHTTHPGDNPC1 | |
| SCHEMBL9562411 | 0.95 | MEN1 (0.39) | MAPTGAAHTTHPGDNPC1 | |
| SCHEMBL9562630 | 0.94 | MAPT (0.41) | MAPTGAALMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | claimed |
| US-5248447-A | 2,3-difluorohydroquinone derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-09-28 | — | — | US | disclosed |