⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550566 | 1.00 | — | — | |
| SCHEMBL8953082 | 0.89 | — | — | |
| SCHEMBL9562831 | 0.89 | — | — | |
| SCHEMBL9562815 | 0.89 | — | — | |
| SCHEMBL8953094 | 0.88 | — | — | |
| SCHEMBL8952755 | 0.87 | — | — | |
| SCHEMBL8952767 | 0.87 | — | — | |
| SCHEMBL8952749 | 0.86 | — | — | |
| SCHEMBL8953110 | 0.85 | — | — | |
| SCHEMBL10345723 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202327-A | PHOSPHORUS-CONTAINING HMG-COA REDUCTASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1993-04-13 | — | — | US | claimed |
| US-5202327-A | PHOSPHORUS-CONTAINING HMG-COA REDUCTASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0522431-A1 | Phophorus-containing HMG-COA reductase inhibitors | E.R. SQUIBB & SONS, INC. (US) | 1993-01-13 | — | — | EP | disclosed |