Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.53 |
| ▸ | BCHE | P06276 | 9/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MLNR | O43193 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563314 | 0.89 | BCHE (0.53) | DRD2SLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL9563263 | 0.83 | BCHE (0.52) | DRD2SLC6A4ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL9563254 | 0.83 | BCHE (0.51) | DRD2SLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL9563296 | 0.82 | BCHE (0.48) | DRD2SLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL9563285 | 0.81 | BCHE (0.46) | DRD2SLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL9563179 | 0.81 | BCHE (0.56) | DRD2SLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL9563272 | 0.81 | BCHE (0.53) | DRD2SLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL9591248 | 0.80 | BCHE (0.47) | DRD2SLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL9563339 | 0.80 | BCHE (0.55) | DRD2SLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL9563267 | 0.80 | BCHE (0.53) | DRD2SLC6A4ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |