Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 10/20 | 0.59 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563238 | 0.97 | CYP2D6 (0.65) | CYP2D6CYP2C19CYP1A2KDM4EBCHE | |
| SCHEMBL9563349 | 0.96 | CYP2D6 (0.64) | CYP2D6CYP2C19CYP1A2KDM4EBCHE | |
| SCHEMBL9563218 | 0.95 | CYP2D6 (0.56) | CYP2D6CYP2C19CYP1A2KDM4EBCHE | |
| SCHEMBL9563212 | 0.94 | CYP2D6 (0.55) | CYP2D6CYP2C19CYP1A2KDM4EBCHE | |
| SCHEMBL9563337 | 0.94 | KDM4E (0.57) | CYP2D6CYP2C19CYP1A2KDM4EBCHE | |
| SCHEMBL9563189 | 0.94 | BCHE (0.57) | CYP2D6CYP2C19CYP1A2KDM4EBCHE | |
| SCHEMBL9563220 | 0.93 | CYP2D6 (0.57) | CYP2D6CYP2C19CYP1A2KDM4EBCHE | |
| SCHEMBL9563379 | 0.92 | CYP2D6 (0.55) | CYP2D6CYP2C19CYP1A2KDM4EBCHE | |
| SCHEMBL9563275 | 0.92 | CYP2D6 (0.52) | CYP2D6CYP2C19CYP1A2KDM4EBCHE | |
| SCHEMBL9563237 | 0.92 | CYP2D6 (0.52) | CYP2D6CYP2C19CYP1A2KDM4EBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |