Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.37 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9155150 | 0.95 | CA1 (0.38) | CA1GABRR1GABRR2BLMGABRR3 | |
| Acetic Acid SCHEMBL9155097 | 0.80 | GABRR1 (0.46) | GABRR1GABRR2BLMGABRR3LMNA | |
| Acetic Acid SCHEMBL2771587 | 0.80 | GABRR1 (0.46) | GABRR1GABRR2BLMGABRR3LMNA | |
| Acetic Acid SCHEMBL8032115 | 0.73 | CA1 (0.53) | CA1GABRR1BLMLMNATDP1 | |
| SCHEMBL11769 | 0.72 | — | — | |
| SCHEMBL1351840 | 0.72 | — | — | |
| SCHEMBL1691477 | 0.72 | — | — | |
| Acetic Acid SCHEMBL9300914 | 0.71 | CA1 (0.50) | CA1GABRR1BLMLMNACA4 | |
| Acetic Acid SCHEMBL245760 | 0.70 | CA1 (0.57) | CA1GABRR1BLMLMNATDP1 | |
| Acetic Acid SCHEMBL9988251 | 0.70 | CA1 (0.57) | CA1GABRR1BLMLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551757-A1 | Processing solution for silver halide colour photographic materials | KONICA CORPORATION (JP) | 1993-07-21 | — | — | EP | disclosed |
| EP-0547796-A1 | Solid chemicals for processing silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1993-06-23 | — | — | EP | disclosed |