SCHEMBL9563759

SCHEMBL9563759

CCOc1ccc(-c2ccc(-c3ccc(-c4ccc(OCC)cc4)c(F)c3F)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.56
TDP1 Q9NUW8 2/20 0.47
MAPT P10636 1/20 0.47
TSHR P16473 1/20 0.47
FFAR1 O14842 1/20 0.46
FFAR4 Q5NUL3 1/20 0.46
RAB9A P51151 5/20 0.45
KDM4E B2RXH2 5/20 0.45
NPC1 O15118 4/20 0.45
ALDH1A1 P00352 4/20 0.45
LMNA P02545 1/20 0.45
XDH P47989 1/20 0.45
LTA4H P09960 2/20 0.44
SMN1; SMN2 Q16637 4/20 0.42
HPGD P15428 3/20 0.42
TP53 P04637 3/20 0.42
HSD17B10 Q99714 3/20 0.41
GAA P10253 1/20 0.41
ALOX15 P16050 1/20 0.41
MPI P34949 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9492786 0.93 NQO1 (0.48) NQO1TDP1MAPTTSHRFFAR1
SCHEMBL9563850 0.93 NQO1 (0.48) NQO1TDP1MAPTTSHRFFAR1
SCHEMBL9563724 0.91 CYP2D6 (0.53) NQO1FFAR1FFAR4RAB9AKDM4E
SCHEMBL9563761 0.91 NQO1 (0.47) NQO1TDP1MAPTTSHRFFAR1
SCHEMBL9564006 0.91 FFAR1 (0.47) NQO1TDP1MAPTFFAR1FFAR4
SCHEMBL16248152 0.91 NQO1 (0.50) NQO1TDP1MAPTTSHRFFAR1
SCHEMBL17897366 0.91 NQO1 (0.50) NQO1TDP1MAPTTSHRFFAR1
SCHEMBL22788361 0.91 NQO1 (0.50) NQO1TDP1MAPTRAB9AKDM4E
SCHEMBL24025302 0.89 NQO1 (0.48) NQO1TDP1MAPTTSHRFFAR1
SCHEMBL9563895 0.88 NQO1 (0.44) NQO1TDP1MAPTTSHRFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5273680-A A chiral tilted smectic liquid crystal based on terphenyls MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1993-12-28 US disclosed