Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLR1 | P15328 | 5/20 | 0.45 |
| ▸ | SLC19A1 | P41440 | 5/20 | 0.45 |
| ▸ | SLC46A1 | Q96NT5 | 5/20 | 0.45 |
| ▸ | GART | P22102 | 2/20 | 0.43 |
| ▸ | TYMS | P04818 | 6/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | FOLR2 | P14207 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564162 | 0.91 | FOLR1 (0.47) | FOLR1SLC19A1SLC46A1GARTTYMS | |
| SCHEMBL9564209 | 0.89 | FOLR1 (0.47) | FOLR1SLC19A1SLC46A1GARTTYMS | |
| SCHEMBL9564170 | 0.89 | FOLR1 (0.47) | FOLR1SLC19A1SLC46A1GARTTYMS | |
| SCHEMBL9564256 | 0.89 | FOLR1 (0.49) | FOLR1SLC19A1SLC46A1GARTTYMS | |
| SCHEMBL9564196 | 0.89 | FOLR1 (0.47) | FOLR1SLC19A1SLC46A1GARTTYMS | |
| SCHEMBL9564271 | 0.89 | FOLR1 (0.47) | FOLR1SLC19A1SLC46A1GARTTYMS | |
| SCHEMBL9564239 | 0.88 | FOLR1 (0.46) | FOLR1SLC19A1SLC46A1GARTTYMS | |
| SCHEMBL9564236 | 0.88 | FOLR1 (0.46) | FOLR1SLC19A1SLC46A1GARTTYMS | |
| SCHEMBL9564179 | 0.87 | FOLR1 (0.46) | FOLR1SLC19A1SLC46A1GARTTYMS | |
| SCHEMBL9564233 | 0.87 | FOLR1 (0.46) | FOLR1SLC19A1SLC46A1GARTTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0549291-A1 | Thymidylate synthase inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |