Benzo[D]Oxazole

Benzo[D]Oxazole

SCHEMBL9564246

C=Cc1ccccc1.c1ccc2ocnc2c1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
TSHR P16473 1/20 0.50
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
CTNNB1 P35222 2/20 0.38
WNT3A P56704 2/20 0.38
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
GAA P10253 2/20 0.35
ESR1 P03372 1/20 0.33
PTPN2 P17706 1/20 0.33
PTPN1 P18031 1/20 0.33
PTPN5 P54829 1/20 0.33
DYRK1A Q13627 2/20 0.33
PDGFRB P09619 1/20 0.32
PDGFRA P16234 1/20 0.32
KDM4E B2RXH2 2/20 0.31
TGFBR1 P36897 1/20 0.31
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL4620916 0.85 PDGFRB (0.44) ALDH1A1NPC1RAB9ASMN1; SMN2CTNNB1
(Z)-1,2-Diphenylethene SCHEMBL4688325 0.85 PDGFRB (0.44) ALDH1A1NPC1RAB9ASMN1; SMN2CTNNB1
(Z)-1,2-Diphenylethene SCHEMBL6418573 0.85 PDGFRB (0.44) ALDH1A1NPC1RAB9ASMN1; SMN2CTNNB1
(Z)-1,2-Diphenylethene SCHEMBL1125602 0.85 PDGFRB (0.44) ALDH1A1NPC1RAB9ASMN1; SMN2CTNNB1
Benzo[D]Oxazole SCHEMBL27505135 0.84 NPC1 (0.46) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
Benzo[D]Oxazole SCHEMBL5921455 0.82 NPC1 (0.41) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
Benzo[D]Oxazole SCHEMBL29083043 0.82 NPC1 (0.45) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
Benzo[D]Oxazole SCHEMBL2385440 0.82 NPC1 (0.43) ALDH1A1TSHRNPC1RAB9ASMN1; SMN2
Benzo[D]Oxazole SCHEMBL7903 0.82
Benzo[D]Oxazole SCHEMBL2724328 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106018579-B The separation method and detection method of benzoxazole fluorescent bleaches in a kind of polystyrene 上海瀚海检测技术股份有限公司 2018-05-15 CN claimed
EP-0543779-A1 Process for optical bleaching of hydrophobic textile material with disperse optical brightness in supercritical CO2 CIBA-GEIGY AG (CH) 1993-05-26 EP claimed
CN-106018579-B The separation method and detection method of benzoxazole fluorescent bleaches in a kind of polystyrene 上海瀚海检测技术股份有限公司 2018-05-15 CN disclosed
CN-106018579-A Separation method and detection method for benzoxazole fluorescent brightener in polystyrene 上海瀚海检测技术股份有限公司 2016-10-12 CN disclosed
CN-1038943-C Detergent compositions containing polyhydroxy fatty acid amide and alkyl sulfonate surfactants PROCTER & GAMBLE (US) 1998-07-01 CN disclosed
CN-1035828-C Ployhydroxy fatty acid amide surfactants to enhance enzyme performance PROCTER & GAMBLE (US) 1997-09-10 CN disclosed
CN-1031721-C Detergent containing sulfate and polyhydroxy fatty acid amide surfactants PROCTER & GAMBLE (US) 1996-05-01 CN disclosed
CN-1030926-C Polyhydroxy fatty acid amides in polycarboxylate built detergents PROCTER & GAMBLE (US) 1996-02-07 CN disclosed
CN-1029320-C Detergent compositions with polyhydroxy fatty amide surfactant and polymeric dispersing agent PROCTER & GAMBLE (US) 1995-07-12 CN disclosed
CN-1072950-A Detergent formulation PROCTER & GAMBLE (US) 1993-06-09 CN disclosed
EP-0543779-A1 Process for optical bleaching of hydrophobic textile material with disperse optical brightness in supercritical CO2 CIBA-GEIGY AG (CH) 1993-05-26 EP disclosed
CN-1061431-A The detergent composition that contains polyhydroxy fatty acid amide surfactants and polymeric dispersant PROCTER & GAMBLE (US) 1992-05-27 CN disclosed
CN-1061244-A Polyhydroxy fatty acid amide in the polycarboxylate built detergent PROCTER & GAMBLE (US) 1992-05-20 CN disclosed
CN-1061041-A The detergent composition that contains polyhydroxy fatty acid amide and alkyl sulfonate surfactants PROCTER & GAMBLE (US) 1992-05-13 CN disclosed
CN-1061042-A Be used to improve the polyhydroxy fatty acid amide surfactant of enzyme performance PROCTER & GAMBLE (US) 1992-05-13 CN disclosed
US-4158658-A Bichromophoric benzoxazole-styrene ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1979-06-19 US disclosed
US-4158658-A Bichromophoric benzoxazole-styrene ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1979-06-19 US disclosed
US-4158658-A Bichromophoric benzoxazole-styrene ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1979-06-19 US disclosed
US-4075162-A BICHROMOPHORIC BENZOXAZOLE-STYRENE ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed
US-4075162-A BICHROMOPHORIC BENZOXAZOLE-STYRENE ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-02-21 US disclosed