SCHEMBL9564571

SCHEMBL9564571

Brc1[nH]nc(C2CN3CCC2CC3)c1Br

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9486233 0.92 CHRM2 (0.38)
SCHEMBL9489609 0.76 CHRM2 (0.36)
SCHEMBL9486019 0.72 CHRNA7 (0.41) CHRNA7
SCHEMBL2123369 0.66 CHRNA7 (0.41) CHRNA7
SCHEMBL2124192 0.63
SCHEMBL6627525 0.61 CHRNA7 (0.52) CHRNA7
SCHEMBL6200423 0.61 CHRM2 (0.44) CHRNA7
SCHEMBL9225384 0.61
SCHEMBL9459257 0.61
SCHEMBL7811502 0.61 CHRM2 (0.43) CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0525879-A1 Pyrazole derivatives Akzo Nobel N.V. (NL) 1993-02-03 EP disclosed