Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 7/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | RGS4 | P49798 | 2/20 | 0.31 |
| ▸ | RGS8 | P57771 | 1/20 | 0.31 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440674 | 0.90 | KAT2B (0.63) | KAT2BFAAHMGLLRGS4RGS8 | |
| SCHEMBL204793 | 0.89 | KAT2B (0.61) | KAT2BFAAHMGLLRGS4RGS8 | |
| SCHEMBL8444108 | 0.89 | KAT2B (0.61) | KAT2BFAAHMGLLRGS4RGS8 | |
| SCHEMBL13837721 | 0.89 | KAT2B (0.61) | KAT2BFAAHMGLLRGS4RGS8 | |
| SCHEMBL8445189 | 0.89 | KAT2B (0.61) | KAT2BFAAHMGLLRGS4RGS8 | |
| SCHEMBL8444109 | 0.88 | KAT2B (0.66) | KAT2BFAAHMGLLRGS4RGS8 | |
| Hydrochloric Acid SCHEMBL9130658 | 0.87 | KAT2B (0.59) | KAT2BFAAHMGLLRGS4RGS8 | |
| SCHEMBL1276432 | 0.84 | KAT2B (0.51) | KAT2BFAAHMGLLRGS4RGS8 | |
| SCHEMBL8440049 | 0.83 | KAT2B (0.70) | KAT2BFAAHMGLLRGS4RGS8 | |
| SCHEMBL2127234 | 0.82 | KAT2B (0.52) | KAT2BFAAHMGLLRGS4RGS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539091-A1 | Novel bis-isothiazolones and the use thereof as microbicides | ROHM AND HAAS COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |