Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9236395 | 0.89 | DHODH (0.33) | DHODHPDE2A | |
| SCHEMBL8492241 | 0.88 | STAT1 (0.34) | PDE4BSTAT1DHODHPDE2A | |
| SCHEMBL8887517 | 0.87 | STAT1 (0.33) | STAT1NAMPTDHODHPDE2A | |
| SCHEMBL9115598 | 0.87 | DHODH (0.35) | DHODH | |
| SCHEMBL6559424 | 0.86 | CNR2 (0.33) | NAMPTDHODHPDE2A | |
| SCHEMBL8886658 | 0.85 | CNR2 (0.31) | PDE4BDHODHPDE2A | |
| SCHEMBL9115912 | 0.83 | DHODH (0.33) | DHODH | |
| SCHEMBL8488423 | 0.83 | RXFP1 (0.34) | PDE4B | |
| SCHEMBL8886617 | 0.82 | PDE2A (0.31) | STAT1NAMPTPDE2A | |
| SCHEMBL8887238 | 0.81 | BTK (0.32) | PDE4BDHODHPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560483-A1 | 4 Benzopyl isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-09-15 | — | — | EP | claimed |
| EP-0560483-A1 | 4 Benzopyl isoxazole derivatives and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-09-15 | — | — | EP | disclosed |