Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL9305890 | 0.85 | ATM (0.50) | — | |
| Iodide SCHEMBL9306597 | 0.85 | — | — | |
| Iodide SCHEMBL9306171 | 0.85 | — | — | |
| Iodide SCHEMBL9308068 | 0.85 | — | — | |
| Iodide SCHEMBL9305723 | 0.85 | — | — | |
| Iodide SCHEMBL9307267 | 0.84 | — | — | |
| SCHEMBL9308501 | 0.80 | HPGD (0.47) | — | |
| Iodide SCHEMBL9309259 | 0.79 | — | — | |
| Iodide SCHEMBL9306673 | 0.78 | — | — | |
| Iodide SCHEMBL9307951 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208247-A | Antianaphylactic agents or septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| EP-0530444-A1 | Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1993-03-10 | — | — | EP | disclosed |