SCHEMBL9565764

SCHEMBL9565764

Clc1ccc(-c2csc3ccccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 4/20 0.49
CYP2A6 P11509 4/20 0.46
HDAC2 Q92769 1/20 0.42
CYP1A2 P05177 1/20 0.41
PRKDC P78527 1/20 0.41
PTGER2 P43116 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM5 P08912 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
MAPT P10636 2/20 0.40
HTT P42858 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ANO1 Q5XXA6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23555986 0.88 ERN1 (0.54) ERN1CYP2A6HDAC2PRKDCCHRM2
SCHEMBL5766614 0.84 ERN1 (0.51) ERN1CYP2A6HDAC2CYP1A2PRKDC
SCHEMBL5848721 0.84 CYP2A6 (0.52) ERN1CYP2A6HDAC2CYP1A2PRKDC
SCHEMBL31092063 0.84 CYP2A6 (0.52) ERN1CYP2A6HDAC2CYP1A2PRKDC
SCHEMBL1772093 0.81 ERN1 (0.49) ERN1CYP2A6HDAC2PRKDCCHRM2
SCHEMBL5370456 0.81 ERN1 (0.56) ERN1CYP2A6HDAC2CYP1A2PRKDC
SCHEMBL7384280 0.81 MAOB (0.52) ERN1CYP2A6HDAC2PRKDCPTGER2
SCHEMBL7504214 0.79 ERN1 (0.55) ERN1CYP2A6HDAC2CYP1A2PRKDC
SCHEMBL24368388 0.79 ERN1 (0.48) ERN1CYP2A6HDAC2PRKDCCHRM2
SCHEMBL26325717 0.79 ERN1 (0.48) ERN1CYP2A6HDAC2PRKDCCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0526951-A1 3-Phenyl benzo b thiophenes as pesticidal compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-02-10 EP disclosed