Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | TDO2 | P48775 | 2/20 | 0.51 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9353200 | 0.99 | IDO1 (0.53) | IDO1TDO2IDO2SLC6A2SLC6A3 | |
| SCHEMBL4189035 | 0.92 | TSHR (0.45) | IDO1TDO2IDO2SLC6A2SLC6A3 | |
| SCHEMBL4192982 | 0.91 | HRH1 (0.43) | IDO1TDO2IDO2SLC6A2SLC6A3 | |
| SCHEMBL1802062 | 0.84 | DRD3 (0.59) | SLC6A2SLC6A3SLC6A4KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL2476701 | 0.82 | MAPK1 (0.60) | SLC6A2SLC6A3SLC6A4KCNH2CYP2D6 | |
| SCHEMBL9257208 | 0.82 | IDO1 (0.51) | IDO1TDO2IDO2SLC6A2SLC6A3 | |
| SCHEMBL4189112 | 0.82 | SLC6A2 (0.48) | SLC6A2SLC6A3SLC6A4KCNH2CYP2D6 | |
| SCHEMBL12064955 | 0.82 | IDO1 (0.50) | IDO1TDO2SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL8537416 | 0.82 | DRD3 (0.59) | SLC6A2SLC6A3KCNH2CYP2D6CHRM2 | |
| SCHEMBL12064967 | 0.78 | DRD3 (0.52) | SLC6A2SLC6A3SLC6A4KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529365-A1 | Diarylmethoxypiperidine derivatives | Kaken Pharmaceutical Co., Ltd. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5190959-A | Antihistamines, antiallergens, treatment of ischemic heart disease | KAKEN PHARMACEUTICAL CO. LTD. (JP) | 1993-03-02 | — | — | US | disclosed |