⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2044640 | 0.64 | — | — | |
| SCHEMBL2040308 | 0.62 | — | — | |
| SCHEMBL2044530 | 0.61 | — | — | |
| SCHEMBL2042011 | 0.61 | — | — | |
| SCHEMBL23346801 | 0.61 | — | — | |
| SCHEMBL2040931 | 0.60 | — | — | |
| SCHEMBL2046977 | 0.60 | — | — | |
| SCHEMBL2045661 | 0.60 | — | — | |
| SCHEMBL2043185 | 0.60 | — | — | |
| SCHEMBL2040170 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535528-A1 | Antibacterial 5-Nitro-1-methyl-imidazolyl-3-terbutyl-2-hydroxy-aryl-carbinols | EURORESEARCH S.r.L. (IT) | 1993-04-07 | — | — | EP | disclosed |
| EP-0103100-B1 | 1-METHYL-5-NITRO-IMIDAZOLINE DERIVATIVES AND THERAPEUTIC COMPOSITIONS WHICH CONTAIN THEM AS ACTIVE PRINCIPLE | EURORESEARCH S.R.L. (IT) | 1987-10-07 | — | — | EP | disclosed |
| US-4476138-A | 1-Methyl-5-nitro-(2-substituted)-2H-imidazole derivatives, and use as bactericidal and protozoacidal agents | FARMATIS S.R.L. (IT) | 1984-10-09 | — | — | US | disclosed |
| EP-0103100-A1 | 1-Methyl-5-nitro-imidazoline derivatives and therapeutic compositions which contain them as active principle | EURORESEARCH S.R.L. (IT) | 1984-03-21 | — | — | EP | disclosed |
| EP-0103100-A1 | 1-Methyl-5-nitro-imidazoline derivatives and therapeutic compositions which contain them as active principle | EURORESEARCH S.R.L. (IT) | 1984-03-21 | — | — | EP | disclosed |