SCHEMBL9567200

SCHEMBL9567200

C=CCOC(=O)N1C[C@@H](SC(c2ccccc2)(c2ccccc2)c2ccccc2)C[C@H]1/C=C\CN1C(=O)c2ccccc2C1=O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.41
CHRM1 P11229 1/20 0.34
FAAH O00519 3/20 0.34
CASP3 P42574 1/20 0.33
MGLL Q99685 1/20 0.33
ALDH1A1 P00352 2/20 0.31
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
F2 P00734 2/20 0.31
ELANE P08246 2/20 0.31
CTSG P08311 1/20 0.31
POLB P06746 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9594709 1.00 NPSR1 (0.41) NPSR1CHRM1FAAHCASP3MGLL
SCHEMBL9567204 1.00 NPSR1 (0.41) NPSR1CHRM1FAAHCASP3MGLL
SCHEMBL9594702 1.00 NPSR1 (0.41) NPSR1CHRM1FAAHCASP3MGLL
SCHEMBL9567202 0.86 CHRM1 (0.38) CHRM1FAAHMGLLALDH1A1LMNA
SCHEMBL9567199 0.86 CHRM1 (0.38) CHRM1FAAHMGLLALDH1A1LMNA
SCHEMBL9567198 0.86 CHRM1 (0.38) CHRM1FAAHMGLLALDH1A1LMNA
SCHEMBL9567211 0.86 CHRM1 (0.37) CHRM1FAAHMGLLALDH1A1LMNA
SCHEMBL9567208 0.86 CHRM1 (0.37) CHRM1FAAHMGLLALDH1A1LMNA
SCHEMBL9567228 0.85 NPSR1 (0.44) NPSR1CHRM1FAAHMGLLALDH1A1
SCHEMBL9567224 0.85 NPSR1 (0.44) NPSR1CHRM1FAAHMGLLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0522504-A1 2-(2-substituted pyrrolidinylthio)-carbapenem derivatives Banyu Pharmaceutical Co., Ltd. (JP) 1993-01-13 EP disclosed