Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246824 | 1.00 | HTT (0.37) | HTT | |
| SCHEMBL8717681 | 0.81 | HTT (0.41) | HTT | |
| SCHEMBL9246559 | 0.81 | HTT (0.41) | HTT | |
| SCHEMBL9249387 | 0.81 | GBA1 (0.35) | HTT | |
| SCHEMBL8714764 | 0.81 | GBA1 (0.35) | HTT | |
| SCHEMBL8719623 | 0.75 | SPHK1 (0.38) | — | |
| SCHEMBL9241715 | 0.75 | SPHK1 (0.38) | — | |
| SCHEMBL9241716 | 0.75 | SPHK1 (0.38) | — | |
| SCHEMBL8714663 | 0.71 | TSHR (0.33) | HTT | |
| SCHEMBL9241753 | 0.69 | GLB1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524439-A1 | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-01-27 | — | — | EP | claimed |