Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567708 | 1.00 | EPHX2 (0.36) | EPHX2GBA1TRPV1CNR1CNR2 | |
| SCHEMBL9567695 | 0.79 | TRPV1 (0.38) | EPHX2TRPV1CNR1CNR2 | |
| SCHEMBL9567697 | 0.79 | TRPV1 (0.38) | EPHX2TRPV1CNR1CNR2 | |
| SCHEMBL9567721 | 0.77 | HTR2C (0.41) | EPHX2GBA1 | |
| SCHEMBL9250532 | 0.75 | GBA1 (0.42) | EPHX2GBA1 | |
| SCHEMBL9243674 | 0.75 | GBA1 (0.42) | EPHX2GBA1 | |
| SCHEMBL9246825 | 0.75 | GBA1 (0.43) | EPHX2GBA1 | |
| SCHEMBL9249282 | 0.75 | GBA1 (0.43) | EPHX2GBA1 | |
| SCHEMBL9567689 | 0.74 | TRPV1 (0.43) | TRPV1CNR1CNR2 | |
| SCHEMBL9567681 | 0.74 | TRPV1 (0.43) | TRPV1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524439-A1 | Novel cyclohexane and tetrahydropyran derivatives and antifungal compositions containing these derivatives | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-01-27 | — | — | EP | claimed |