Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568056 | 0.82 | PTGIR (0.40) | HTTALDH1A1KDM4EPTGIRLMNA | |
| SCHEMBL9047848 | 0.81 | PTGIR (0.43) | ALDH1A1KDM4EKMT2AMEN1PTGIR | |
| SCHEMBL5321084 | 0.76 | HTT (0.48) | HTTALDH1A1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL29484110 | 0.73 | HTT (0.54) | HTTALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL8858455 | 0.73 | PTGIR (0.61) | PTGIR | |
| SCHEMBL29706163 | 0.73 | HTT (0.54) | HTTALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL242244 | 0.73 | HTT (0.54) | HTTALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL2792830 | 0.73 | HTT (0.54) | HTTALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL29608780 | 0.73 | HTT (0.54) | HTTALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL2796237 | 0.73 | HTT (0.54) | HTTALDH1A1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |