Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 2/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9567953 | 0.89 | GBA1 (0.55) | GBA1CYP19A1HTR1ASIGMAR1PLAU | |
| SCHEMBL10530881 | 0.87 | IDO1 (0.50) | GBA1CYP19A1MAPTCHRM2CHRM4 | |
| SCHEMBL10616682 | 0.82 | GBA1 (0.52) | GBA1CYP19A1HTR1ASIGMAR1PLAU | |
| SCHEMBL15701675 | 0.81 | CYP19A1 (0.54) | GBA1CYP19A1HTR1ASIGMAR1PLAU | |
| SCHEMBL1689627 | 0.81 | CYP19A1 (0.54) | GBA1CYP19A1HTR1ASIGMAR1PLAU | |
| SCHEMBL6570371 | 0.81 | CYP19A1 (0.54) | GBA1CYP19A1HTR1ASIGMAR1PLAU | |
| SCHEMBL11076774 | 0.81 | GBA1 (0.55) | GBA1CYP19A1HTR1ASIGMAR1PLAU | |
| SCHEMBL5849555 | 0.80 | GBA1 (0.51) | GBA1CYP19A1HTR1ASIGMAR1MAPT | |
| SCHEMBL5661239 | 0.80 | CYP19A1 (0.56) | GBA1CYP19A1HTR1ADRD2DRD4 | |
| SCHEMBL4803094 | 0.79 | GBA1 (0.57) | GBA1CYP19A1HTR1ASIGMAR1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542203-A2 | Fused benzeneoxyacetic acid derivatives as PGl2 receptor agonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-05-19 | — | — | EP | disclosed |