Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 8/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.42 |
| ▸ | PLG | P00747 | 3/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.39 |
| ▸ | F2 | P00734 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9568126 | 1.00 | ST14 (0.42) | ST14PRSS1PRSS2PRSS3PLG | |
| SCHEMBL9568102 | 0.85 | TSHR (0.39) | ALDH1A1LMNA | |
| SCHEMBL9568097 | 0.85 | TSHR (0.39) | ALDH1A1LMNA | |
| SCHEMBL8410171 | 0.84 | CFTR (0.48) | ST14PRSS1PRSS2PRSS3PLG | |
| Hydrochloric Acid SCHEMBL9568153 | 0.81 | ST14 (0.40) | ST14PRSS1PRSS2PRSS3PLG | |
| SCHEMBL8410563 | 0.81 | KDM1A (0.48) | ST14PRSS1PRSS2PRSS3PLG | |
| SCHEMBL9568196 | 0.80 | F2 (0.44) | ST14PRSS1PRSS2PRSS3PLG | |
| SCHEMBL9568200 | 0.80 | F2 (0.44) | ST14PRSS1PRSS2PRSS3PLG | |
| Hydrochloric Acid SCHEMBL9568164 | 0.79 | F2 (0.43) | ST14PRSS1PRSS2PRSS3PLG | |
| SCHEMBL9568220 | 0.79 | ST14 (0.40) | ST14PRSS1PRSS2PRSS3PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574808-A1 | Amidine-biphenyl derivatives, process for their production & medical preparation containing them | Dr. Karl Thomae GmbH (DE) | 1993-12-22 | — | — | EP | disclosed |