SCHEMBL9568876

SCHEMBL9568876

O=Cc1csc(C(F)F)n1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 1/20 0.40
MAPT P10636 1/20 0.38
ALDH1A1 P00352 1/20 0.34
CCR1 P32246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3556404 0.75 MAPT (0.38) HTR2BMAPTALDH1A1
SCHEMBL16742562 0.75 MAPT (0.45) HTR2BMAPTALDH1A1
SCHEMBL1051061 0.72 MAPT (0.40) HTR2BMAPTALDH1A1
SCHEMBL4505751 0.71 HTR2B (0.40) HTR2BMAPTALDH1A1CCR1
SCHEMBL9381730 0.71 MAPT (0.36) HTR2BMAPTALDH1A1
SCHEMBL28854137 0.71 SMN1; SMN2 (0.30)
SCHEMBL30344 0.69
SCHEMBL548197 0.69
SCHEMBL13999711 0.68 MAPT (0.39) HTR2BMAPTALDH1A1
SCHEMBL20130304 0.68 HTR2B (0.35) HTR2BMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117800944-A Pyridine amide derivative, pharmaceutical composition containing same and medical application of pharmaceutical composition 苏州阿尔脉生物科技有限公司 2024-04-02 CN disclosed
EP-0556123-A1 Pyrethrinoid esters of thiazolylalcohols, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1993-08-18 EP disclosed