Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 7/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADA | P00813 | 1/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | PGK2 | P07205 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29722605 | 0.91 | ADORA2A (0.51) | ADORA2ASLC29A1ADORA3ADORA1ADORA2B | |
| SCHEMBL930687 | 0.91 | ADORA2A (0.51) | ADORA2ASLC29A1ADORA3ADORA1ADORA2B | |
| SCHEMBL19644951 | 0.91 | ADORA2A (0.51) | ADORA2ASLC29A1ADORA3ADORA1ADORA2B | |
| SCHEMBL17109574 | 0.91 | ADORA2A (0.51) | ADORA2ASLC29A1ADORA3ADORA1ADORA2B | |
| SCHEMBL18656252 | 0.91 | ADORA2A (0.51) | ADORA2ASLC29A1ADORA3ADORA1ADORA2B | |
| SCHEMBL13030120 | 0.91 | ADORA2A (0.51) | ADORA2ASLC29A1ADORA3ADORA1ADORA2B | |
| SCHEMBL15948782 | 0.91 | ADORA2A (0.51) | ADORA2ASLC29A1ADORA3ADORA1ADORA2B | |
| SCHEMBL17117139 | 0.91 | ADORA2A (0.51) | ADORA2ASLC29A1ADORA3ADORA1ADORA2B | |
| SCHEMBL16001101 | 0.91 | ADORA2A (0.51) | ADORA2ASLC29A1ADORA3ADORA1ADORA2B | |
| SCHEMBL14785979 | 0.91 | ADORA2A (0.51) | ADORA2ASLC29A1ADORA3ADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576227-A2 | 2'-Deoxy-2',2'-difluoro(2,6,8-substituted) purine nucleosides having anti-viral and anti-cancer activity and intermediates | ELI LILLY AND COMPANY (US) | 1993-12-29 | — | — | EP | claimed |
| EP-0576227-A2 | 2'-Deoxy-2',2'-difluoro(2,6,8-substituted) purine nucleosides having anti-viral and anti-cancer activity and intermediates | ELI LILLY AND COMPANY (US) | 1993-12-29 | — | — | EP | disclosed |