Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9569634 | 1.00 | FGFR1 (0.38) | FGFR1SLC22A6POLA1ADRA2ANISCH | |
| SCHEMBL9569628 | 1.00 | FGFR1 (0.38) | FGFR1SLC22A6POLA1ADRA2ANISCH | |
| SCHEMBL9569689 | 0.88 | FGFR1 (0.34) | FGFR1SLC22A6POLA1 | |
| SCHEMBL9569681 | 0.88 | FGFR1 (0.34) | FGFR1SLC22A6POLA1 | |
| SCHEMBL9569697 | 0.88 | FGFR1 (0.34) | FGFR1SLC22A6POLA1 | |
| SCHEMBL9569759 | 0.85 | FGFR1 (0.44) | FGFR1SLC22A6POLA1 | |
| SCHEMBL9569760 | 0.85 | FGFR1 (0.44) | FGFR1SLC22A6POLA1 | |
| SCHEMBL9569761 | 0.85 | FGFR1 (0.44) | FGFR1SLC22A6POLA1 | |
| SCHEMBL9569545 | 0.84 | FGFR1 (0.51) | FGFR1SLC22A6POLA1 | |
| SCHEMBL9569540 | 0.84 | FGFR1 (0.51) | FGFR1SLC22A6POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532423-A1 | Novel unsaturated acyclic phosphonate derivatives of purine and pyrimidine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-03-17 | — | — | EP | disclosed |