Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.65 |
| ▸ | DRD4 | P21917 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558691 | 0.94 | HRH3 (0.69) | DRD2DRD4DRD3HRH3KCNH2 | |
| SCHEMBL9570637 | 0.94 | HRH3 (0.69) | DRD2DRD4DRD3HRH3KCNH2 | |
| SCHEMBL10554981 | 0.94 | HRH3 (0.69) | DRD2DRD4DRD3HRH3KCNH2 | |
| SCHEMBL5390369 | 0.94 | HRH3 (0.69) | DRD2DRD4DRD3HRH3KCNH2 | |
| SCHEMBL10556391 | 0.94 | HRH3 (0.69) | DRD2DRD4DRD3HRH3KCNH2 | |
| SCHEMBL10559291 | 0.94 | HRH3 (0.69) | DRD2DRD4DRD3HRH3KCNH2 | |
| SCHEMBL9570561 | 0.94 | HRH3 (0.69) | DRD2DRD4DRD3HRH3KCNH2 | |
| SCHEMBL6228523 | 0.93 | MAPT (0.65) | DRD2DRD4DRD3HRH3KCNH2 | |
| SCHEMBL21331697 | 0.91 | MAPT (0.57) | DRD2DRD4DRD3HRH3KCNH2 | |
| SCHEMBL2565246 | 0.90 | MAPT (0.67) | DRD2DRD4DRD3HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |