SCHEMBL9570690

SCHEMBL9570690

Fc1ccc(COCC(c2ccc(Cl)cc2)C(F)(F)F)cc1Oc1ccc(C(F)(F)F)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 2/20 0.41
HTR2A P28223 1/20 0.41
KCNH2 Q12809 1/20 0.41
CNR2 P34972 1/20 0.39
FFAR1 O14842 2/20 0.39
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
CACNA1G O43497 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.35
CNR1 P21554 3/20 0.35
TACR1 P25103 2/20 0.34
CACNA1F O60840 1/20 0.34
CACNA1D Q01668 1/20 0.34
CACNA1S Q13698 1/20 0.34
CACNA1C Q13936 1/20 0.34
SCN8A Q9UQD0 2/20 0.34
SCN10A Q9Y5Y9 2/20 0.34
UTS2R Q9UKP6 1/20 0.34
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9570793 0.92 TACR1 (0.39) SLC6A4FFAR1TACR1CACNA1FCACNA1D
SCHEMBL9560399 0.91 TACR1 (0.41) SLC6A4KCNH2FFAR1TACR1CACNA1F
SCHEMBL9862613 0.91 TACR1 (0.41) SLC6A4KCNH2FFAR1TACR1CACNA1F
SCHEMBL9561512 0.90 TACR1 (0.36) FFAR1PPARGPPARATACR1CACNA1F
SCHEMBL9570621 0.89 PPARG (0.33) SLC6A4HTR2AKCNH2FFAR1PPARG
SCHEMBL9862431 0.89 SLC6A4 (0.36) SLC6A4HTR2AKCNH2PPARGCNR1
SCHEMBL9570700 0.89 PPARG (0.33) SLC6A4HTR2AKCNH2FFAR1PPARG
SCHEMBL9862440 0.89 SLC6A4 (0.36) SLC6A4HTR2AKCNH2PPARGCNR1
SCHEMBL9570581 0.89 MAPT (0.46) FFAR1PPARGCACNA1CSCN8ASCN10A
SCHEMBL9560849 0.87 MAPT (0.40) SLC6A4HTR2AKCNH2FFAR1CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed