SCHEMBL9570707

SCHEMBL9570707

FC(F)(F)C(COCc1cccc(Oc2ccccc2)c1)c1ccc2c(c1)CCC2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CETP P11597 8/20 0.40
MAPK14 Q16539 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
POLB P06746 1/20 0.37
GFER P55789 1/20 0.37
PAX8 Q06710 1/20 0.37
KLF5 Q13887 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MGLL Q99685 1/20 0.37
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
TACR1 P25103 2/20 0.36
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
FFAR1 O14842 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9560456 0.86 MAPK14 (0.35) CETPMAPK14NPC1RAB9APOLB
SCHEMBL9570878 0.85 MAPK14 (0.34) CETPMAPK14TACR1FFAR1
SCHEMBL7930457 0.84 CETP (0.45) CETPMGLLTACR1FFAR1
SCHEMBL9804480 0.83 FDFT1 (0.43) CETPMAPK14MGLL
SCHEMBL9570765 0.82 CETP (0.44) CETPMGLLFFAR1
SCHEMBL9570718 0.81 CETP (0.40) CETPMGLLTACR1FFAR1SMN1; SMN2
SCHEMBL9570753 0.81 CETP (0.41) CETPMGLLFFAR1
SCHEMBL9560683 0.81 KDM4E (0.50) CETPPRMT5WDR77TACR1KDM4E
SCHEMBL9560903 0.81 FFAR1 (0.46) CETPTACR1KDM4EALDH1A1FFAR1
SCHEMBL9560487 0.81 PPARG (0.47) CETPTACR1ALDH1A1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed