Cyclohexanone Oxime

Cyclohexanone Oxime

SCHEMBL9570768

CC1([SiH3])CCCCC1=NO.ON=C1CCCCC1.ON=C1CCCCC1

nearest known ligand 0.52

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
CASP1 P29466 1/20 0.52
GAA P10253 2/20 0.32
ALDH1A1 P00352 2/20 0.32
POLB P06746 1/20 0.32
LMNA P02545 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexanone Oxime SCHEMBL9570734 0.74 TSHR (0.47) TSHRCASP1
Cyclohexanone Oxime SCHEMBL1720578 0.72 TSHR (0.88) TSHRCASP1ALDH1A1POLBLMNA
Cyclohexanone Oxime SCHEMBL3260818 0.72 TSHR (0.88) TSHRCASP1ALDH1A1POLBLMNA
SCHEMBL3474721 0.72 TSHR (1.00) TSHRCASP1ALDH1A1LMNAL3MBTL1
SCHEMBL3190316 0.72 TSHR (1.00) TSHRCASP1ALDH1A1LMNAL3MBTL1
Cyclohexanone Oxime SCHEMBL37995 0.72
SCHEMBL1026335 0.72 TSHR (1.00) TSHRCASP1ALDH1A1LMNAL3MBTL1
Cyclohexanone Oxime SCHEMBL11884936 0.72 TSHR (1.00) TSHRCASP1ALDH1A1LMNAL3MBTL1
SCHEMBL1025656 0.72 TSHR (1.00) TSHRCASP1ALDH1A1LMNAL3MBTL1
SCHEMBL3472281 0.72 TSHR (1.00) TSHRCASP1ALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0565318-A1 Room temperature curable organopolysiloxane compositions and process of making them Shin-Etsu Chemical Co., Ltd. (JP) 1993-10-13 EP claimed
EP-0565318-A1 Room temperature curable organopolysiloxane compositions and process of making them Shin-Etsu Chemical Co., Ltd. (JP) 1993-10-13 EP disclosed
EP-0082324-B1 PRODUCING OXIMINOSILANES, OXIMINOGERMANES AND OXIMINOSTANNANES ALLIED CORPORATION (US) 1987-01-14 EP disclosed
US-4400527-A Producing oximinosilanes, oximinogermanes and oximinostannanes ALLIED CORPORATION (US) 1983-08-23 US disclosed
EP-0082324-A2 Producing oximinosilanes, oximinogermanes and oximinostannanes ALLIED CORPORATION (US) 1983-06-29 EP disclosed
US-4371682-A CROSSLINKING AGENTS OF ORGANOOXYSILOXANEOXIMCS; HIGH-SPEED MOISTURE CURING TOSHIBA SILICONES, LTD. (JP) 1983-02-01 US disclosed