SCHEMBL9570809

SCHEMBL9570809

Fc1ccc(C(COCc2cccc(Oc3ccc(Cl)cc3)c2)C(F)(F)F)cc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CETP P11597 7/20 0.42
PPARG P37231 2/20 0.41
PPARA Q07869 2/20 0.41
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.38
FDFT1 P37268 2/20 0.37
TACR1 P25103 2/20 0.36
FFAR4 Q5NUL3 2/20 0.36
FFAR1 O14842 1/20 0.35
MMP13 P45452 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9560890 0.95 CETP (0.44) CETPPPARGPPARAALDH1A1LMNA
SCHEMBL9560487 0.93 PPARG (0.47) CETPPPARGPPARAALDH1A1LMNA
SCHEMBL9570765 0.92 CETP (0.44) CETPFDFT1FFAR4FFAR1
SCHEMBL9570598 0.90 CETP (0.41) CETPPPARGPPARAALDH1A1LMNA
SCHEMBL9560931 0.90 CETP (0.41) CETPPPARGPPARAALDH1A1LMNA
SCHEMBL9560416 0.90 CETP (0.43) CETPPPARGPPARAALDH1A1LMNA
SCHEMBL9570717 0.89 CETP (0.40) CETPFDFT1TACR1FFAR4FFAR1
SCHEMBL9570791 0.89 CETP (0.40) CETPFDFT1TACR1FFAR4FFAR1
SCHEMBL9862593 0.88 FFAR1 (0.44) CETPPPARGPPARAALDH1A1LMNA
SCHEMBL118655 0.88 FFAR1 (0.44) CETPPPARGPPARAALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0545891-A2 Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-06-09 EP disclosed
US-4840971-A INSECTICIDES, MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-06-20 US disclosed
EP-0240978-A2 Ether compounds, process for their preparation, compositions containing the same and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-10-14 EP disclosed