Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570855 | 0.90 | MEN1 (0.51) | MEN1KMT2ACACNA1FPOLBMAPK1 | |
| SCHEMBL9570738 | 0.79 | MEN1 (0.42) | MEN1KMT2ACACNA1FPOLBMAPK1 | |
| SCHEMBL9411094 | 0.75 | MEN1 (0.49) | MEN1KMT2ACACNA1FPOLBMAPK1 | |
| SCHEMBL9411021 | 0.75 | MEN1 (0.49) | MEN1KMT2ACACNA1FPOLBMAPK1 | |
| SCHEMBL9570909 | 0.73 | MEN1 (0.35) | MEN1KMT2ACACNA1FPOLBMAPK1 | |
| SCHEMBL10679796 | 0.73 | MEN1 (0.50) | MEN1KMT2ACACNA1FPOLBMAPK1 | |
| SCHEMBL10679936 | 0.72 | MEN1 (0.56) | MEN1KMT2ACACNA1FPOLBMAPK1 | |
| SCHEMBL10679869 | 0.71 | MEN1 (0.53) | MEN1KMT2ACACNA1FPOLBMAPK1 | |
| SCHEMBL10682678 | 0.71 | MEN1 (0.48) | MEN1KMT2ACACNA1FPOLBMAPK1 | |
| SCHEMBL10679416 | 0.71 | MEN1 (0.72) | MEN1KMT2ACACNA1FPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550903-A1 | Quinolone- and naphthyridone carboxylic acid derivatives as antibacterial agents | BAYER AG (DE) | 1993-07-14 | — | — | EP | disclosed |