Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | POLB | P06746 | 3/20 | 0.72 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.72 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | TTR | P02766 | 2/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | IGF1R | P08069 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | GSK3B | P49841 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | GSK3A | P49840 | 1/20 | 0.57 |
| ▸ | NAT1 | P18440 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570599 | 0.87 | MEN1 (0.74) | KMT2AMEN1ALDH1A1POLBPLA2G1B | |
| SCHEMBL9570595 | 0.87 | MEN1 (0.74) | KMT2AMEN1ALDH1A1POLBPLA2G1B | |
| SCHEMBL2420684 | 0.85 | MEN1 (0.70) | KMT2AMEN1ALDH1A1POLBPLA2G1B | |
| SCHEMBL2420687 | 0.85 | MEN1 (0.70) | KMT2AMEN1ALDH1A1POLBPLA2G1B | |
| SCHEMBL2420688 | 0.85 | MEN1 (0.70) | KMT2AMEN1ALDH1A1POLBPLA2G1B | |
| SCHEMBL1247460 | 0.84 | MEN1 (1.00) | KMT2AMEN1ALDH1A1POLBPLA2G1B | |
| SCHEMBL12155710 | 0.84 | MEN1 (1.00) | KMT2AMEN1ALDH1A1POLBPLA2G1B | |
| SCHEMBL1247458 | 0.84 | MEN1 (1.00) | KMT2AMEN1ALDH1A1POLBPLA2G1B | |
| SCHEMBL13846503 | 0.83 | IGF1R (0.69) | KMT2AMEN1ALDH1A1POLBPLA2G1B | |
| SCHEMBL18102906 | 0.83 | MEN1 (0.75) | KMT2AMEN1ALDH1A1POLBPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |