Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.62 |
| ▸ | PRKCA | P17252 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 3/20 | 0.60 |
| ▸ | CDK4 | P11802 | 2/20 | 0.60 |
| ▸ | CCND1 | P24385 | 2/20 | 0.60 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.60 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.60 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.59 |
| ▸ | CDK9 | P50750 | 2/20 | 0.59 |
| ▸ | PTPRC | P08575 | 1/20 | 0.58 |
| ▸ | GSK3A | P49840 | 2/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | RGS12 | O14924 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28505491 | 0.84 | CDK2 (0.60) | GSK3BPRKCACDK2CDK4CCND1 | |
| SCHEMBL9572022 | 0.83 | GSK3B (0.64) | GSK3BPRKCACDK2CDK4CCND1 | |
| SCHEMBL6097272 | 0.82 | CDK4 (0.55) | GSK3BPRKCACDK2CDK4CCND1 | |
| SCHEMBL7508106 | 0.80 | CCNT1 (0.61) | GSK3BPRKCACDK2CDK4CCND1 | |
| SCHEMBL29419482 | 0.80 | CCNT1 (0.61) | GSK3BPRKCACDK2CDK4CCND1 | |
| SCHEMBL28514472 | 0.79 | GSK3B (0.55) | GSK3BPRKCACDK2CDK4CCND1 | |
| SCHEMBL9572024 | 0.77 | GSK3B (0.71) | GSK3BPRKCACDK2CDK4CCND1 | |
| SCHEMBL7195024 | 0.77 | CCNT1 (0.76) | GSK3BPRKCACDK2CDK4CCND1 | |
| SCHEMBL30319850 | 0.77 | GSK3B (1.00) | GSK3BPRKCACDK2CDK4CCND1 | |
| SCHEMBL5682596 | 0.77 | GSK3B (1.00) | GSK3BPRKCACDK2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| CN-110437124-B | Preparation method of indoloquinone derivative | 中国科学院成都有机化学有限公司 | 2020-12-22 | — | — | CN | disclosed |
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |