Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 3/20 | 0.45 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070877 | 0.91 | TAAR1 (0.59) | HDAC1HDAC3HDAC2HDAC6TAAR1 | |
| SCHEMBL7564465 | 0.91 | TAAR1 (0.59) | HDAC1HDAC3HDAC2HDAC6TAAR1 | |
| SCHEMBL8077779 | 0.91 | TAAR1 (0.59) | HDAC1HDAC3HDAC2HDAC6TAAR1 | |
| SCHEMBL8063292 | 0.91 | TAAR1 (0.59) | HDAC1HDAC3HDAC2HDAC6TAAR1 | |
| SCHEMBL8077486 | 0.91 | TAAR1 (0.59) | HDAC1HDAC3HDAC2HDAC6TAAR1 | |
| SCHEMBL8062071 | 0.91 | TAAR1 (0.59) | HDAC1HDAC3HDAC2HDAC6TAAR1 | |
| SCHEMBL8072554 | 0.89 | TAAR1 (0.61) | HDAC1HDAC3HDAC2HDAC6TAAR1 | |
| SCHEMBL11773030 | 0.87 | CYP3A4 (0.49) | TAAR1CALM1FAAHMGLL | |
| SCHEMBL11773043 | 0.87 | CYP3A4 (0.49) | TAAR1CALM1FAAHMGLL | |
| SCHEMBL11776870 | 0.87 | CYP3A4 (0.49) | TAAR1CALM1FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243076-A | Adrenergic stimulant intermediates | GLAXO GROUP LTD. | 1993-09-07 | — | — | US | disclosed |
| US-5225445-A | Respiratory system disorders | GLAXO GROUP LTD. | 1993-07-06 | — | — | US | disclosed |
| US-5126375-A | Asthma, chronic bronchitis | GLAXO GROUP LTD. (GB) | 1992-06-30 | — | — | US | disclosed |
| US-5091422-A | Treating inflammatory or allergic skin disease, lowering gastric acidity | GLAXO GROUP LIMITED (GB) | 1992-02-25 | — | — | US | disclosed |
| US-4992474-A | Adrenergic stimulants | GLAXO GROUP LTD. (GB) | 1991-02-12 | — | — | US | disclosed |