Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262777 | 1.00 | IDO1 (0.52) | IDO1MEN1KMT2AHRH3TDP1 | |
| SCHEMBL9257411 | 1.00 | IDO1 (0.52) | IDO1MEN1KMT2AHRH3TDP1 | |
| SCHEMBL7099472 | 0.98 | IDO1 (0.53) | IDO1MEN1KMT2AHRH3TDP1 | |
| SCHEMBL454150 | 0.96 | TDP1 (0.53) | IDO1MEN1KMT2AHRH3TDP1 | |
| SCHEMBL9574235 | 0.96 | TDP1 (0.53) | IDO1MEN1KMT2AHRH3TDP1 | |
| SCHEMBL9257077 | 0.96 | TDP1 (0.53) | IDO1MEN1KMT2AHRH3TDP1 | |
| SCHEMBL9258098 | 0.96 | TDP1 (0.53) | IDO1MEN1KMT2AHRH3TDP1 | |
| SCHEMBL7621746 | 0.96 | TDP1 (0.53) | IDO1MEN1KMT2AHRH3TDP1 | |
| SCHEMBL6942905 | 0.96 | TDP1 (0.53) | IDO1MEN1KMT2AHRH3TDP1 | |
| SCHEMBL10477865 | 0.96 | TDP1 (0.53) | IDO1MEN1KMT2AHRH3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243076-A | Adrenergic stimulant intermediates | GLAXO GROUP LTD. | 1993-09-07 | — | — | US | disclosed |
| US-5225445-A | Respiratory system disorders | GLAXO GROUP LTD. | 1993-07-06 | — | — | US | disclosed |
| US-5126375-A | Asthma, chronic bronchitis | GLAXO GROUP LTD. (GB) | 1992-06-30 | — | — | US | disclosed |
| US-5091422-A | Treating inflammatory or allergic skin disease, lowering gastric acidity | GLAXO GROUP LIMITED (GB) | 1992-02-25 | — | — | US | disclosed |
| US-4992474-A | Adrenergic stimulants | GLAXO GROUP LTD. (GB) | 1991-02-12 | — | — | US | disclosed |