SCHEMBL9575145

SCHEMBL9575145

CCCCCCCCCCCCCCCl.CCCCP(CCCC)CCCC

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.68
ALDH1A1 P00352 2/20 0.68
TDP1 Q9NUW8 1/20 0.50
THRB P10828 1/20 0.42
FAAH O00519 2/20 0.36
DNM1 Q05193 7/20 0.36
PLA2G1B P04054 1/20 0.34
HSP90AA1 P07900 1/20 0.34
RAD52 P43351 1/20 0.34
ATG4B Q9Y4P1 1/20 0.34
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC22A1 O15245 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2333085 1.00 TSHR (0.68) TSHRALDH1A1TDP1THRBFAAH
SCHEMBL4935174 0.97 TSHR (0.63) TSHRALDH1A1TDP1THRBFAAH
SCHEMBL8665060 0.89 TSHR (0.56) TSHRALDH1A1TDP1THRBFAAH
1,2-Dichloroethane SCHEMBL9225958 0.86 TSHR (0.50) TSHRALDH1A1TDP1THRBLMNA
Ethyl Chloride SCHEMBL11466896 0.83 TSHR (0.50) TSHRALDH1A1TDP1THRBDNM1
SCHEMBL8047790 0.83 TSHR (0.53) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL7158110 0.83 TSHR (0.53) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL5474314 0.83 TSHR (0.53) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL5473266 0.83 TSHR (0.53) TSHRALDH1A1THRBDNM1LMNA
SCHEMBL6286000 0.83 TSHR (0.53) TSHRALDH1A1THRBDNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544347-A1 Composition for protecting timber from fungal growth FMC CORPORATION (UK) LIMITED (GB) 1993-06-02 EP claimed
CN-117820176-A Sulfoxide-based benzotrifluoride compound 上海泰初化工技术有限公司 2024-04-05 CN disclosed
CN-117820180-A Sulfonyl trifluoro toluene compound 上海泰初化工技术有限公司 2024-04-05 CN disclosed
EP-3529233-A1 METHOD FOR PRODUCING 3-ALKYLSULFANYL-2-CHLORO-N-(1-ALKYL-1H-TETRAZOL-5-YL)-4-TRIFLUOROMETHYL-BENZAMIDES Bayer CropScience Aktiengesellschaft (DE) 2019-08-28 EP disclosed
EP-0544347-A1 Composition for protecting timber from fungal growth FMC CORPORATION (UK) LIMITED (GB) 1993-06-02 EP disclosed