Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619588 | 0.84 | CYP2C19 (0.59) | CYP3A4CYP2C19HIF1ACYP1A2CYP2C9 | |
| SCHEMBL5929605 | 0.81 | CYP1A2 (0.53) | KCNA5CYP3A4CYP2C19HIF1ACYP1A2 | |
| SCHEMBL11631869 | 0.79 | KCNA5 (0.65) | KCNA5CYP3A4CYP2C19HIF1ACYP1A2 | |
| SCHEMBL5929544 | 0.78 | KCNA5 (0.46) | KCNA5CYP3A4CYP2C19HIF1ACYP1A2 | |
| SCHEMBL27989626 | 0.78 | KCNA5 (0.46) | KCNA5CYP3A4CYP2C19HIF1ACYP1A2 | |
| SCHEMBL11469797 | 0.76 | KCNA5 (0.46) | KCNA5CYP3A4CYP2C19HIF1ACYP1A2 | |
| SCHEMBL4336663 | 0.76 | KCNA5 (1.00) | KCNA5CYP3A4CYP2C19HIF1ACYP1A2 | |
| SCHEMBL11613454 | 0.75 | KCNA5 (0.47) | KCNA5CYP3A4CYP2C19HIF1ACYP1A2 | |
| SCHEMBL17047076 | 0.75 | CYP1A2 (0.50) | KCNA5CYP3A4CYP2C19HIF1ACYP1A2 | |
| SCHEMBL11493107 | 0.75 | KCNA5 (0.59) | KCNA5CYP3A4CYP2C19HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528172-A1 | (2-Alkyl-3-pyridyl)methylpiperazine derivatives as PAF antagonists | J. URIACH & CIA. S.A. (ES) | 1993-02-24 | — | — | EP | disclosed |