Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575583 | 0.98 | IDO1 (0.37) | IDO1TDO2PTGER4PTGER3PTGER2 | |
| SCHEMBL10597079 | 0.98 | IDO1 (0.37) | IDO1TDO2PTGER4PTGER3PTGER2 | |
| SCHEMBL9575838 | 0.98 | IDO1 (0.37) | IDO1TDO2PTGER4PTGER3PTGER2 | |
| SCHEMBL9450427 | 0.98 | IDO1 (0.37) | IDO1TDO2PTGER4PTGER3PTGER2 | |
| SCHEMBL8270831 | 0.95 | — | — | |
| SCHEMBL10768301 | 0.82 | TP53 (0.39) | IDO1TDO2PTGER4PTGER3PTGER2 | |
| SCHEMBL12054853 | 0.80 | IDO1 (0.33) | IDO1TDO2 | |
| SCHEMBL6085440 | 0.76 | IDO1 (0.32) | IDO1TDO2PTGER4PTGER3PTGER2 | |
| SCHEMBL10607112 | 0.76 | METAP1 (0.43) | — | |
| SCHEMBL6759876 | 0.76 | METAP1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258183-B1 | PROCESS FOR THE PREPARATION OF 5-AMINO-4-HYDROXYVALERIC-ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |
| US-5010189-A | Processes for the preparation of 5-amino-4-hydroxy-valeric acid derivatives | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | disclosed |
| US-4898977-A | Processes for the preparation of 5-amino-4-hydroxyvaleric acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0258183-A2 | Process for the preparation of 5-amino-4-hydroxyvaleric-acid derivatives | CIBA-GEIGY AG (CH) | 1988-03-02 | — | — | EP | disclosed |