Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 7/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575571 | 0.83 | GSK3B (0.51) | GSK3BCLK1DYRK1ADYRK1BVNN1 | |
| SCHEMBL9575857 | 0.82 | GSK3B (0.47) | GSK3BMAPK14MAPTHDAC8 | |
| SCHEMBL11057542 | 0.81 | GSK3B (0.50) | GSK3BCLK1DYRK1ADYRK1BVNN1 | |
| SCHEMBL4201889 | 0.80 | ATM (0.63) | GSK3BCLK1DYRK1ADYRK1BVNN1 | |
| SCHEMBL9575847 | 0.79 | F2 (0.44) | GSK3BVNN1MAPT | |
| SCHEMBL7473918 | 0.79 | GSK3B (0.48) | GSK3BCLK1DYRK1ADYRK1BVNN1 | |
| SCHEMBL9575546 | 0.78 | NPC1 (0.47) | GSK3BVNN1MAPK14 | |
| SCHEMBL9797519 | 0.78 | GSK3B (0.53) | GSK3BCLK1DYRK1ADYRK1BVNN1 | |
| Water SCHEMBL28352748 | 0.77 | MAPT (0.61) | MAPTHDAC8 | |
| SCHEMBL5226711 | 0.77 | MAPK14 (0.50) | GSK3BCLK1DYRK1ADYRK1BVNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367671-B1 | NOVEL BETA-D-PHENYLTHIOXYLOSIDES, THEIR METHOD OF PREPARATION AND THEIR USE AS PHARMACEUTICALS | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-07-28 | — | — | EP | disclosed |
| US-4960758-A | Antithrombotics | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-02 | — | — | US | disclosed |
| EP-0367671-A2 | Novel beta-D-phenylthioxylosides, their method of preparation and their use as pharmaceuticals | FOURNIER INDUSTRIE ET SANTE (FR) | 1990-05-09 | — | — | EP | disclosed |