Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575610 | 1.00 | GRIK1 (0.46) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14304330 | 1.00 | GRIK1 (0.46) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9858396 | 1.00 | GRIK1 (0.46) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2031190 | 0.88 | SLC1A3 (0.48) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8096822 | 0.88 | SLC1A3 (0.48) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6871010 | 0.88 | SLC1A3 (0.48) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2031192 | 0.88 | SLC1A3 (0.48) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8101229 | 0.88 | SLC1A3 (0.48) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2035309 | 0.88 | SLC1A3 (0.48) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL2035310 | 0.88 | SLC1A3 (0.48) | GRIK1GRIK2SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258183-B1 | PROCESS FOR THE PREPARATION OF 5-AMINO-4-HYDROXYVALERIC-ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |
| US-5010189-A | Processes for the preparation of 5-amino-4-hydroxy-valeric acid derivatives | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | disclosed |
| US-4898977-A | Processes for the preparation of 5-amino-4-hydroxyvaleric acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0258183-A2 | Process for the preparation of 5-amino-4-hydroxyvaleric-acid derivatives | CIBA-GEIGY AG (CH) | 1988-03-02 | — | — | EP | disclosed |