Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | PLA2G2C | Q5R387 | 7/20 | 0.53 |
| ▸ | PRKCA | P17252 | 3/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.46 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.46 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.46 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942036 | 1.00 | USP2 (0.54) | USP2PLA2G2CPRKCAPRKCEPRKCQ | |
| SCHEMBL10938399 | 1.00 | USP2 (0.54) | USP2PLA2G2CPRKCAPRKCEPRKCQ | |
| SCHEMBL10941567 | 1.00 | USP2 (0.54) | USP2PLA2G2CPRKCAPRKCEPRKCQ | |
| SCHEMBL10938100 | 1.00 | USP2 (0.54) | USP2PLA2G2CPRKCAPRKCEPRKCQ | |
| SCHEMBL11128122 | 1.00 | USP2 (0.54) | USP2PLA2G2CPRKCAPRKCEPRKCQ | |
| SCHEMBL10941176 | 1.00 | USP2 (0.54) | USP2PLA2G2CPRKCAPRKCEPRKCQ | |
| SCHEMBL10940410 | 1.00 | USP2 (0.54) | USP2PLA2G2CPRKCAPRKCEPRKCQ | |
| SCHEMBL10937869 | 0.87 | USP2 (0.51) | USP2PLA2G2CPRKCAPRKCEPRKCQ | |
| SCHEMBL10941828 | 0.87 | USP2 (0.51) | USP2PLA2G2CPRKCAPRKCEPRKCQ | |
| SCHEMBL10943913 | 0.87 | USP2 (0.56) | USP2PLA2G2CPRKCAPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5187293-A | Blood platelet activating factor inhibitors | HOFFMANN-LA ROCHE INC. (US) | 1993-02-16 | — | — | US | disclosed |
| EP-0147768-B1 | GLYCERIN DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1989-02-08 | — | — | EP | disclosed |
| US-4731373-A | BLOOD PLATELET ACTIVATING FACTOR | HOFFMAN-LA ROCHE INC. (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0147768-A2 | Glycerin derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-07-10 | — | — | EP | disclosed |