Iodide

Iodide

SCHEMBL9575683

O=C(O)CCC[n+]1ccccc1.[I-]

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 7/20 0.54
BCHE P06276 7/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170298 0.98 BCHE (0.56) BCHEACHE
Hydrochloric Acid SCHEMBL9575972 0.95 BCHE (0.54) BCHEACHE
SCHEMBL4471140 0.91 BCHE (0.61) BCHEACHE
SCHEMBL5529631 0.89 BCHE (0.65) BCHEACHE
SCHEMBL5541357 0.89 BCHE (0.65) BCHEACHE
SCHEMBL5533799 0.89 BCHE (0.65) BCHEACHE
SCHEMBL5535651 0.89 BCHE (0.65) BCHEACHE
SCHEMBL5538030 0.89 BCHE (0.65) BCHEACHE
SCHEMBL5538412 0.89 BCHE (0.65) BCHEACHE
SCHEMBL5536162 0.89 BCHE (0.65) BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0147768-B1 GLYCERIN DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1989-02-08 EP claimed
US-4731373-A BLOOD PLATELET ACTIVATING FACTOR HOFFMAN-LA ROCHE INC. (US) 1988-03-15 US claimed
US-5187293-A Blood platelet activating factor inhibitors HOFFMANN-LA ROCHE INC. (US) 1993-02-16 US disclosed
US-4731373-A BLOOD PLATELET ACTIVATING FACTOR HOFFMAN-LA ROCHE INC. (US) 1988-03-15 US disclosed